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within the early 90s, Novell had here certifications accessible: CNA-licensed Novell Administrator, CNE-licensed Novell Engineer, and the ECNE-business certified Novell Engineer (the MCNE-grasp CNE has in view that replaced the ECNE). The CNA, CNE, and MCNE are nevertheless accessible. moreover, Novell has the CDE-licensed listing Engineer, the CNI-licensed Novell teacher, and the MCNI-master certified Novell instructor. Novell's CIP-certified internet skilled certification has recently merged with Prosoft's CIW. i will subsist able to focus on the CIW alternate options in an upcoming article. additionally, because this is now not a coach's discussion board, i cannot address the CNI or MCNI. if you maintain a question concerning the CNI or MCNI, suppose free to drop me an e-mail or attach up a remark, and that i can subsist pleased to reply. I can also subsist reached at email@example.com. If sufficient interest is expressed, I will subsist joyful to maneuver lots of the quite a lot of trainer options that exist in the present IT market, together with the CNI and MCNI, in a future essay.
The CNA is the entry-degree Novell certification. The CNA is designed for these constructing workstations, managing clients and organizations, administering a printing ambiance, and automating community access. it is a one-check, one-path certification. counting on the working system that you aid, that you can rate the CNA in NetWare 5, IntraNetWare, and GroupWise 5. The CNA in NetWare three and GroupWise four could subsist retired on the proximate of 2001. if you're administering a GroupWise 5.5 atmosphere (GroupWise is Novell's e mail device), you can also rate the CNA.
The CNE is one in sum Novell's Premier certifications. reckoning on the CNE song that you simply pursue, you are going to choose either six or seven assessments. The CNE is designed for networking experts who are chargeable for retaining their networks up and operating. These are the folks charged with designing a TCP/IP internetwork and designing a directory functions implementation. There are five tracks which are currently provided, two of which may subsist retired on the proximate of 2001. These tracks are NetWare 5, GroupWise 5 and IntraNetWare. (The NetWare three and GroupWise four tracks can subsist retired.) in order to rate the NetWare 5 CNE, you should pass six tests: a) NetWare 5.1 Administration; b) NetWare 5.1 superior Administration; c) NetWare 5.1 Design and Implementation; d) Networking technologies; e) carrier and help; and f) one optionally available. The electives encompass a) desktop administration with ZENworks; b) computer administration with ZENworks for computers three; c) information superhighway protection management with BorderManager; d) network administration the expend of ManageWise 2.7; e) community management the expend of ManageWise 2.6; f) TCP/IP for Networking specialists; g) Integrating NetWare and home windows NT; or h) GroupWise 5.5 Administration. IntraNetWare and GroupWise 5.5 CNEs maintain one test to absorb addition to their earlier CNE necessities: either the NetWare 5.1 superior Administration check or the NetWare 4.11 to NetWare 5.1 supersede examination. This requirement is as a result of Novell needs sum legacy CNEs to help their core competencies to the NetWare 5.1 platform.
Novell has these days introduced the requirements for the brand new NetWare 6 CNE song. As of this writing, NetWare 6 CNEs could maintain seven checks to flow: a) eDirectory Administration with NetWare 6; b) CompTIA's network + examination; c) NetWare 6 superior Administration; d) NDS Design and Implementation; e) provider and assist; f) TCP/IP for Networking authorities; and g) computer administration for ZENworks with computers 3. Novell is additionally planning other changes to the CNE certification with the intention to revolve across the conception of skillability Certificates. check Novell's internet web page http://www.novell.com/training/certinfo/ for constructing details.
One question that arises as Novell displays the NetWare 6 CNE requirements is here: when you are already pursuing the NetWare 5 CNE, when you finish it, or for those who wait for the NetWare 6 tune to roll out? according to Novell's historical past, in case you maintain made an investment of time and funds within the NetWare 5 tune, conclude it. which you could await that each the NetWare 5 and NetWare 6 tracks will subsist accessible as certification alternate options once the NetWare 6 tune rolls out for a broad length. if you rate the NetWare 5 CNE, Novell's past record has shown that you're going to only should choose a separate supersede examination. I had to choose a separate update exam when IntranetWare came out with the intention to help from NetWare 4.1 when NetWare 5.0 came out and when NetWare 5.1 rolled out. here is now not Microsoft, for which you should choose an additional seven assessments to upgrade from NT three.fifty one to four.0; then you definately requisite to choose an extra seven tests when you upgrade from NT 4.0 to windows 2000.
The MCNE is designed for these people who are answerable for integrating NDS with the structures of alternative companies. The MCNE music is undergoing a broad overhaul. as much as July 31, 2001, Novell had six tracks that ended in the MCNE. These tracks protected management, Connectivity, Messaging, web/Intranet solutions, NetWare and UNIX Integration, and NetWare and windows NT Integration. i used to subsist in a position to rate the MCNE in administration, Connectivity, Messaging, and NT Integration. valuable April 15, 2001, Novell streamlined the six tracks into a separate MCNE tune. To rate the MCNE now, candidates ought to maintain the NetWare 5 CNE after which must flux four assessments: one core requirement and three electives. The core requirement is TCP/IP for Networking experts. The three electives will also subsist any three of here: a) GroupWise 6 advanced Administration; b) GroupWise 5 internet entry and Connectivity version 2; c) Integrating NetWare and home windows NT; d) Integrating NDS eDirectory and energetic listing; e) network administration using Managewise 2.7; f) cyber web safety management with BorderManager; g) desktop administration with ZENworks; h) desktop management with ZENworks for pcs 3; or i) Managing NetScape commercial enterprise Server for NetWare. Novell also lately announced extra adjustments to the MCNE track when NetWare 6 rolls out. The adjustments will encompass two CompTIA tests. master CNE candidates may subsist required to slide CompTIA's Server+ and IT assignment+ tests. master CNEs upgrading from NetWare 5 could subsist required to pass the IT task+ exam as a continuing certification requirement. assess Novell's internet web site http://www.novell.com/schooling/certinfo/ for the latest information.
The CDE, one in every of Novell's most up-to-date certifications, is designed for advanced champion persons who should recognize a route to integrate and troubleshoot directory-service concerns. The focus of this certification is the vitality of directory capabilities, even with the father or mother platform: NetWare, UNIX, or W2K. NetWare 5 CNEs can rate the CDE by passing two tests: a) the advanced NDS tackle and Diagnostics test; and b) the directory technologies examine. The advanced NDS tools and Diagnostics examine has a written and functional element. Microsoft MCSEs, Cisco CCIEs and CCNPs, and IBM certified experts can also rate the CDE. They deserve to pass the two up to now mentioned assessments and two extra tests. these checks are: a) NDS Design and Implementation; and b) Microsoft's Designing home windows 2000 directory functions or NetWare 5.1 Administration for Cisco and IBM folks. Microsoft folks can produce a preference from Integrating NDS eDirectory and home windows NT or the Microsoft Designing home windows 2000 listing services test. I haven't yet pursued or earned the CDE. Many who maintain sat in the course of the ILTs and corresponding checks maintain instructed me that the CDE checks are a real test of your competencies and purposeful knowledge. here's some of the few Novell certifications that I finish not currently cling. it's my intent to pursue it someday this 12 months as a result of I believe it will proceed to extend my earning advantage, and it'll continue to validate my present competence set. i will permit you to know how it goes.
January 24, 2000Web posted at: 12:eleven p.m. EST (1711 GMT)
through John Bass and James Robinson, network World notice at various Alliance
(IDG) -- it sum boils prerogative down to what you are hunting for in a community operating system (NOS).
Do you requisite it rawboned and versatile so you can set up it any means you please? in sum probability administration bells and administration whistles are what you requisite so you can installation several hundred servers. Or maybe you want an operating system that is robust ample so that you sleep like a child at nighttime?
The respectable information is that there's a NOS waiting just for you. After the rash of contemporaneous application revisions, they took an in-depth examine 4 of the primary NOSes available on the market: Microsoft's home windows 2000 superior Server, Novell's NetWare 5.1, red Hat application's Linux 6.1 and The Santa Cruz Operation's (SCO) UnixWare 7.1.1. sun declined their invitation to post Solaris since the enterprise says it's engaged on a new edition.
Microsoft's windows 2000 edges out NetWare for the community World Blue Ribbon Award. windows 2000 tops the box with its administration interface, server monitoring tools, storage administration facilities and protection measures.
although, if it's performance you might subsist after, no product got here proximate to Novell's NetWare 5.1's numbers in their exhaustive file service and community benchmarks. With its lightning-speedy engine and Novell's directory-primarily based administration, NetWare presents an outstanding base for an trade community.
We discovered the newest release of pink Hat's commercial Linux bundle led the listing for flexibility as a result of its modular design lets you pare down the working device to fade well with the assignment at hand. additionally, that you can create scripts out of varied Linux instructions to automate projects across a distributed ambiance.
whereas SCO's UnixWare perceived to lag in the back of the pack in terms of file provider performance and NOS-based administration points, its scalability aspects produce it a powerful candidate for operating commercial enterprise applications.The numbers are in
even with the job you saddle your server with, it has to achieve well at studying and writing files and sending them across the network. They designed two benchmark suites to measure each and every NOS in these two classes. To replicate the precise world, their benchmark tests accept as just with a broad sweep of server circumstances.
NetWare was the hands-down leader in their efficiency benchmarking, taking first locality in two-thirds of the file assessments and earning revise billing within the community assessments.
pink Hat Linux adopted NetWare in file efficiency gauge and even outpaced the leader in file checks where the study/write hundreds maintain been small. despite the fact, Linux did not operate smartly handling giant loads - those exams through which there maintain been more than 100 users. below heavier person hundreds, Linux had a bent to stop servicing file requests for a brief length and then delivery up once again.
home windows 2000 tested foul write performance across sum their file assessments. definitely, they institute that its write efficiency turned into about 10% of its study performance. After consulting with both Microsoft and customer/Server options, the author of the Benchmark factory checking out implement they used, they determined that the terrible write performance may well subsist because of two components. One, which they were unable to verify, can subsist a practicable efficiency rigor with the SCSI driver for the hardware they used.
greater massive, though, was an issue with their notice at various software. Benchmark manufacturing unit sends a write-via flag in each of its write requests that is meant to trigger the server to supersede cache, if appropriate, and then obligate a write to disk. When the write to disk happens, the write denomination is released and the next request may also subsist sent.
firstly glance, it regarded as if windows 2000 become the handiest working system to reverence this write-via flag as a result of its write performance turned into so negative. hence, they ran a second circular of write assessments with the flag grew to become off.
With the flag grew to become off, NetWare's write efficiency extended with the aid of 30%. This notice at various proved that Novell does indeed reverence the write-through flag and will write to disk for every write request when that flag is decided. but when the write-via flag is disabled, NetWare writes to disk in a extra efficacious manner with the aid of batching collectively contiguous blocks of data on the cache and writing sum those blocks to disk without delay.
Likewise, crimson Hat Linux's efficiency accelerated by using 10% to 15% when the write-via flag became grew to become off. once they examined the Samba file device code, they discovered that it too honors the write-through flag. The Samba code then finds an top-rated time during the study/write sequence to write to disk.
This 2nd round of file testing proves that home windows 2000 is based on its file device cache to optimize write efficiency. The results of the trying out with the write-through flag off maintain been lots larger - as a righteous deal as 20 instances sooner. youngsters, home windows 2000 nonetheless fell at the back of both NetWare and RedHat Linux within the file write exams when the write-via flag turned into off.
SCO honors the write-via flag by using default, on the grounds that its journaling file tackle is constructed to maximise statistics integrity via writing to disk for sum write requests. The effects in the write tests with the write-via flag on were very corresponding to the check results with the write-through flag turned off.
For the network benchmark, they developed two checks. Their long TCP transaction notice at various measured the bandwidth each and every server can maintain, whereas their brief TCP transaction examine measured every server's means to tackle massive numbers of network periods with petite file transactions.
despite a terrible displaying within the file benchmark, home windows 2000 came out on preempt in the lengthy TCP transaction check. windows 2000 is the only NOS with a multithreaded IP stack, which allows for it to maneuver community requests with numerous processors. Novell and crimson Hat swear they are engaged on integrating this competence into their items.
NetWare and Linux also registered potent long TCP test outcomes, coming in 2nd and third, respectively.
in the short TCP transaction check, NetWare came out the transparent winner. Linux earned second locality despite its want of assist for abortive TCP closes, a route by which an working tackle can promptly cleave down TCP connections. Their testing utility, Ganymede application's Chariot, makes expend of abortive closes in its TCP tests.stepping into administration
As trade networks develop to require greater servers and assist greater conclusion clients, NOS administration tackle spin into crucial elements in preserving networks beneath handle. They appeared at the administration interfaces of each product and drilled down into how every dealt with server monitoring, client administration, file and print management, and storage management.
We institute home windows 2000 and NetWare deliver equally advantageous management interfaces.
Microsoft administration Console (MMC) is the glue that holds many of the home windows 2000 administration performance collectively. This configurable graphical consumer interface (GUI) means that you can snap in Microsoft and third-birthday party applets that personalize its performance. it subsist a two-paned interface, an poor lot like home windows Explorer, with a nested listing on the left and selection details on the appropriate. The console is simple to expend and lets you configure many autochthonous server aspects, together with users, disks, and device settings similar to time and date.
MMC also allows you to implement management policies for organizations of clients and computer systems using energetic directory, Microsoft's new directory provider. From the energetic listing management implement inside MMC, which you can configure clients and alter guidelines.
The community configuration tackle are institute in a part utility that opens in the event you click on on the network locations icon on the laptop. each community interface is listed interior this window. you can add and change protocols and configure, allow and disable interfaces from here with out rebooting.
NetWare offers several interfaces for server configuration and administration. These tools proffer duplicate functionality, however each and every is valuable based from where you are trying to control the device. The gadget Console offers a few tools for server configuration. one of the vital positive is NWConfig, which means that you can trade start-up files, installation device modules and configure the storage subsystem. NWConfig is elementary, intuitive and predictable.
ConsoleOne is a Java-primarily based interface with a brace of graphical tackle for managing and configuring NetWare. Third-celebration administration tackle can plug into ConsoleOne and permit you to control multiple functions. They believe ConsoleOne's interface is benign of unsophisticated, however it works neatly satisfactory for those who should maintain a windows- primarily based supervisor.
Novell also presents a web-accessible management software called NetWare administration Portal, which lets you maneuver NetWare servers remotely from a browser, and NWAdmin32, a relatively fundamental customer-side implement for administering Novell directory functions (NDS) from a home windows 95, ninety eight or NT client.
red Hat's basic methods management interface is referred to as LinuxConf and can Run as a graphical or textual content-based mostly application. The graphical interface, which resembles that of MMC, works well but has some design considerations that produce it tricky to produce expend of at times. for example, for those who Run a setup utility that takes up loads of the monitor, the system resizes the software higher than the computing device dimension.
nonetheless, which you could maneuver fairly a lot the rest on the server from LinuxConf, and you can expend it in the community or remotely over the internet or by the expend of telnet. you could configure tackle parameters comparable to network addresses; file system settings and user money owed; and installation add-on features akin to Samba - which is a carrier that lets home windows customers accept to data residing on a Linux server - and FTP and internet servers. that you could result adjustments with out rebooting the system.
universal, red Hat's interface is efficacious and the underlying tackle are potent and flexible, however LinuxConf lacks the polish of the other vendors' equipment.
SCO Admin is a GUI-based entrance conclusion for roughly 50 SCO UnixWare configuration and management tackle in a separate window. in the event you click on a tool, it brings up the application to control that detail in a part window.
some of SCO's tackle are GUI-based whereas others are text-based. The server required a reboot to practice many of the adjustments. On the plus aspect, that you can control dissimilar UnixWare servers from SCOAdmin.
SCO also presents a efficacious Java-based mostly remote administration implement referred to as WebTop that works out of your browser.a watch on the servers and customers
One Important administration project is monitoring the server itself. Microsoft leads the pack in how smartly you can preserve an eye fixed in your server's internals.
The windows 2000 system pomp screen permits you to view a real-time, running graph of tackle operations, akin to CPU and community utilization, and recollection and disk usage. They used these tools noticeably to investigate the impact of their benchmark exams on the operating equipment. an additional implement called community monitor has a fundamental network packet analyzer that permits you to espy the styles of packets coming into the server. together, these Microsoft utilities may also subsist used to examine performance and capacity across multiple home windows 2000 servers.
NetWare's computer screen utility displays processor utilization, reminiscence usage and buffer utilization on a autochthonous server. in case you understand what to search for, it will also subsist a magnificent implement for diagnosing bottlenecks within the device. learning the that means of each and every of the monitored parameters is just a microscopic of a problem, though.
if you requisite to study performance information across several servers, which you can tap into Novell's net management Portal.
crimson Hat presents the ordinary Linux command-line tools for monitoring the server, such as iostat and vmstat. It has no graphical monitoring equipment.
as with any Unix working device, which you could write scripts to automate these tackle throughout Linux servers. youngsters, these tools are customarily cryptic and require a unreasonable stage of talent to produce expend of readily. a collection of graphical monitoring tackle could subsist an outstanding addition to crimson Hat's Linux distribution.
UnixWare also offers a few monitoring equipment. tackle monitor is UnixWare's primary but limited GUI for monitoring processor and recollection utilization. The sar and rtpm command-line tackle collectively record true-time device utilization of buffer, CPUs and disks. together, these tackle proffer you a superb gauge theory of the load on the server.customer administration
together with managing the server, you ought to manage its clients. it's no dumbfound that the two NOSes that ship with an integrated directory provider topped the bailiwick in customer administration equipment.
We had been capable of configure person permissions via Microsoft's energetic listing and the listing administration device in MMC. that you can group users and computers into organizational units and practice policies to them.
you can control Novell's NDS and NetWare consumers with ConsoleOne, NWAdmin or NetWare management Portal. each and every can create clients, maneuver file house, and set permissions and rights. additionally, NetWare ships with a five-consumer version of Novell's ZENworks device, which offers desktop administration features comparable to hardware and application inventory, software distribution and remote control functions.
purple Hat Linux doesn't present a lot within the route of client administration points. You must maneuver autochthonous users via Unix authorization configuration mechanisms.
UnixWare is similar to pink Hat Linux when it comes to client administration, however SCO offers some home windows binaries on the server to remotely set file and directory permissions from a home windows client, as well as create and change clients and their settings. SCO and purple Hat present champion for the Unix-based community information carrier (NIS). NIS is a shop for community guidance like logon names, passwords and home directories. This integration helps with client administration.handling the staples: File and print
A NOS is nothing without the competence to partake file storage and printers. Novell and Microsoft accumulated revise honors in these areas.
you could with ease add and hold printers in home windows 2000 the expend of the print administration wizard, and you can add file shares using energetic directory administration tools. home windows 2000 additionally presents distributed File capabilities, which allow you to combine data on multiple server into a separate share.
Novell disbursed Print services (NDPS) let you straight away incorporate printers into the network. When NDPS senses a new printer on the network, it defines a Printer Agent that runs on the printer and communicates with NDS. then you definitely expend NDS to silhouette the policies for the new printer.
You silhouette NetWare file services through creating and then mounting a disk quantity, which additionally manages quantity policies.
crimson Hat includes Linux's printtool utility for constructing server-linked and networks printers. that you would subsist able to also expend this GUI to create printcap entries to define printer access.
Linux has a set of command-line file tackle configuration tools for mounting and unmounting partitions. Samba ships with the product and gives some integration for home windows purchasers. you could configure Samba simplest via a cryptic configuration ASCII file - a staid downside.
UnixWare gives a versatile GUI-primarily based printer setup implement referred to as Printer SetUp supervisor. For file and quantity management, SCO presents a device called VisionFS for interoperability with windows consumers. They used VisionFS to enable their NT shoppers to access the UnixWare server. This service turned into handy to configure and use.Storage management
home windows 2000 provides the optimum tools for storage management. Its graphical control Disks implement for local disk configuration contains software RAID management; that you could dynamically add disks to a quantity set while not having to reboot the device. moreover, a signature is written to each of the disks in an array in order that they will also subsist moved to an extra 2000 server without needing to configure the quantity on the brand new server. the brand new server recognizes the drives as individuals of a RAID set and adds the extent to the file tackle dynamically.
NetWare's volume management tool, NWConfig, is convenient to produce expend of, however will also subsist a bit difficult to set up a RAID volume. as soon as they knew what they maintain been doing, they had no problems formatting drives and making a RAID volume. The device looks a microscopic primitive, but they give it elevated marks for functionality and ease of use.
red Hat Linux offers no graphical RAID configuration equipment, but its command line tackle made RAID configuration easy.
To configure disks on the UnixWare server, they used the Veritas extent manager graphical disk and quantity administration device that ships with UnixWare. They had some problems initially getting the device to admire the drives so that they could subsist formatted. They managed to toil across the disk configuration issue using an assortment of command line equipment, after which quantity manager worked smartly.protection
while they did not probe these NOSes notably to expose any safety weaknesses, they did notice at what they offered in safety elements.
Microsoft has made huge strides with home windows 2000 safety. home windows 2000 supports Kerberos public key certificates as its basic authentication mechanism within a site, and allows further authentication with sensible cards. Microsoft offers a protection Configuration implement that integrates with MMC for convenient administration of protection objects in the energetic directory capabilities device, and a new Encrypting File device that permits you to designate volumes on which files are immediately kept the expend of encryption.
Novell added lead for a public-key infrastructure into NetWare 5 using a public certificate schema developed by using RSA security that means that you can tap into NDS to generate certificates.
crimson Hat presents a basic Kerberos authentication mechanism. With crimson Hat Linux, as with most Unix working methods, the community features will also subsist personally controlled to enhance protection. pink Hat offers Pluggable Authentication Modules as a means of allowing you to set authentication guidelines throughout programs working on the server. Passwords are included with a shadow file. red Hat also bundles firewall and VPN services.
UnixWare has a collection of protection tools known as security supervisor that allows you to install various degrees of intrusion protection across your network features, from no restrict to turning sum community services off. it subsist a mighty administration time saver, although you might manually adjust the capabilities to achieve the identical effect.stability and vice tolerance
the most characteristic-wealthy NOS is of microscopic cost if it can't preserve a server up and working. windows 2000 presents utility RAID 0, 1 and 5 configurations to deliver vice tolerance for onboard disk drives, and has a developed-in community load-balancing duty that permits a bunch of servers to seem like one server and partake the identical community identify and IP address. The group decides which server will service each and every request. This not simplest distributes the network load across a brace of servers, it additionally gives vice tolerance in case a server goes down. On a lesser scale, that you could expend Microsoft's Failover Clustering to deliver primary failover features between two servers.
As with NT four.0, windows 2000 gives reminiscence insurance plan, which skill that every procedure runs in its own segment.
There are also backup and repair capabilities bundled with windows 2000.
Novell has an add-on product for NetWare known as Novell Cluster features that means that you can cluster as many as eight servers, sum managed from one vicinity the usage of ConsoleOne, NetWare management Portal or NWAdmin32. but Novell presently presents no clustering items to give load balancing for functions or file features. NetWare has an complicated reminiscence protection scheme to segregate the reminiscence used for the kernel and applications, and a Storage administration services module to supply a particularly bendy backup and repair facility. Backups can also subsist all-inclusive, cowl materials of a quantity or shop a differential photo.
red Hat gives a load-balancing product called piranha with its Linux. This kit gives TCP load balancing between servers in a cluster. There is not any complicated restrict to the variety of servers that you can configure in a cluster. red Hat Linux additionally offers application RAID assist through command line equipment, has reminiscence insurance draw capabilities and offers a rudimentary backup facility.
SCO provides an non-compulsory duty to cluster a few servers in a load-balancing atmosphere with continuous Clustering for a elevated flush of fault-tolerance. currently, continuous Clustering helps six servers in a cluster. UnixWare gives application RAID assist this is managed using SCO's online records manager characteristic. sum the regular RAID stages are supported. laptop buddies' bundled ArcServeIT 6.6 gives backup and repair capabilities. UnixWare has reminiscence insurance draw capabilities.Documentation
as a result of their checking out turned into conducted earlier than windows 2000's normal availability ship date, they maintain been not capable of evaluate its tough-replica documentation. The online documentation offered on a CD is extensive, efficacious and well-equipped, besides the fact that children a web interface could subsist an poor lot less difficult to produce expend of if it gave more than a few sentences at a time for a particular champion theme.
NetWare 5 comes with two manuals: a detailed manual for installing and configuring the NOS with respectable explanations of concepts and contours together with a top flush view of a route to configure them, and a petite spiral-sure booklet of short delivery cards. Novell's on-line documentation is awfully valuable.
red Hat Linux comes with three manuals - an installing guide, a getting begun lead and a reference lead - sum of that are effortless to follow.
regardless of being essentially the most problematic product to installation, UnixWare offers the optimum documentation. It comes with two manuals: a device lead and a getting sum started e book. The gadget lead is a reference for conducting the installing of the working equipment. It does a pretty righteous job of reflecting this painful event. The getting started book is well-written and smartly-prepared. It covers lots of the tools crucial to configure and retain the operating device. SCO's online documentation appears fine and is effortless to observe.Wrapping up
The base line is that these NOSes proffer a broad sweep of features and provide enterprise valued clientele with a mighty deal of alternative involving how each can subsist utilized in any given corporate community.
in case you desire a very good, ordinary intention NOS that can deliver business-class services with sum of the bells and whistles imaginable, then home windows 2000 is the strongest contender. despite the fact, for elevated performance, enterprise file and print functions, their tests exhibit that Novell leads the pack. if you're inclined to pay an improved expense for scalability and reliability, SCO UnixWare would subsist a safe wager. but when you requisite a reasonable preference in order to provide you with naked-bones community features with righteous efficiency, pink Hat Linux can actually fitting the bill.
The option is yours.
Bass is the technical director and Robinson is a senior technical team of workers member at Centennial Networking Labs (CNL) at North Carolina condition school in Raleigh. CNL specializes in performance, skill and contours of networking and server applied sciences and equipment.connected reports:
Debate will focal point on Linux vs. LinuxJanuary 20, 2000Some home windows 2000 PCs will soar the gunJanuary 19, 2000IBM throws Linux lovefestJanuary 19, 2000Corel Linux will Run home windows appsJanuary 10, 2000Novell's eDirectory spans platformsNovember sixteen, 1999New NetWare embraces internet appsNovember 2, 1999Microsoft units a date for home windows 2000October 28, 1999linked IDG.internet stories:
Fusion's forum: rectangular off with the carriers over who has the foremost NOS(community World Fusion)How they did it: details of the trying out(network World Fusion)discover the tuning parameters(network World Fusion)down load the Config data(community World Fusion)The Shootout effects(community World Fusion)Fusion's NOS supplies(network World Fusion)With windows 2000, NT grows up(network World Fusion)Fireworks expected at NOS showdown(community World Fusion)
be aware: Pages will open in a new browser windowexterior websites aren't counseled through CNN Interactive. connected sites:
Novell, Inc.Microsoft Corp.The Santa Cruz Operation, Inc. (SCO)pink Hat, Inc.
word: Pages will open in a new browser windowexterior websites aren't recommended by means of CNN Interactive.
Nasdaq stocks, usually unstable, led the market better beginning in October, on anticipation that a Clinton Presidency would aid smaller corporations. Utilities, then again, are always havens for retirees in search of earnings from elevated dividends and for cash managers too terrorized to dangle the rest more dangerous, however nevertheless expected to retain their funds in stocks. 'A nervous Market'
"it subsist a anxious market," talked about Lawrence R. Rice, chief market strategist at Josephthal, Lyon & Ross. The Dow industrials don't seem to subsist pulling the leisure of the market up after them, he noted, and the bond market rally alerts a enterprise slowdown forward.
issues that gained narrowly outnumbered losers on the big Board the day before today, on ponderous extent of 329.6 million shares.
other analysts took greater reassurance from the disparate fortunes of the market's sectors, noting that these dumping biotechnology shares had been still retaining their cash in shares. "they may subsist simply switching," observed David G. Shulman, chief fairness strategist at Salomon Brothers. "The market's nevertheless awash in money."
That money is now forsaking the Nasdaq market. New public choices, pushed out at checklist tempo on Wall street, maintain left some buyers sentiment bloated. The Nasdaq composite, up greater than 25 percent from early October to early February, has fallen well-nigh 8 p.c when you regard that. greater than half of that decline came within the remaining week.
Mary C. Farrell, a small-stock professional at Paine Webber, spoke of traders maintain been dismayed that President Clinton promised remaining week to aid only the smallest beginning-up groups, which are not the ones present in most portfolios. "Small-cap shares are really too mammoth to harvest the advantages," she talked about. "It become an issue of expectations." Dashed Hopes in Biotechnology
Biotechnology stocks were the bloodiest victims of dashed hopes, as neatly as the Clinton health-care plans. the day before today, Amgen fell 3 1/2, to forty one 1/2; Chiron 5 1/eight, to 45 5/8; Genzyme three 1/four, to 29 1/4, and Biomet 1 1/4, to 11. Synergen plunged 28 5/8, to 13 1/2, in frantic buying and selling, probably the most energetic inventory on any change.
different health-care stocks also suffered, whether on Nasdaq or the big Board, with united states of americaHealthcare off 4, to 39 1/2; Mylan Laboratories falling four 5/8, to 25 3/four; Johnson & Johnson off 1 1/2, to 39 1/eight, and Abbott Laboratories down 1, to 23 1/four.
Nasdaq's leading laptop shares, many up sharply considering that autumn, joined within the retreat in that market. Microsoft misplaced three, to seventy six three/four, and Novell declined 1, to 26 1/2.
The greener scenery of the huge Board featured the shares most sensitive to lessen pastime prices. The 6.01-element profit within the Dow utilities, the greatest factor gain due to the fact that hobby rates plunged after the 1987 market crash, came with not anything of the 15 issues in the general showing a loss. Consolidated Edison, Pacific fuel and electric powered and Philadelphia electric had been among the power corporations gaining a point or more.
The final time the Dow utilities gained extra in percentage phrases changed into on may also 31, 1988, after they rose three.2 % in response to a rally within the credit score market that pushed down bond yields. In regularly occurring, reduce bond yields assist utility stocks, that are primarily bought for their quite unreasonable dividend profits. mobilephone shares Are Up
among mobilephone stocks, GTE and sum the regional Bells but one were also respectable for at the least a degree, and BellSouth was up three/4. investors searching for excessive-yielding stocks and market laggards also alighted on power businesses.
Banks, among the many other beneficiaries of dwindle activity charges, superior strongly, with Suntrust up 1 three/four, to forty six. J. P. Morgan won 2 three/four, to 65, as Merrill Lynch issued a buy recommendation.
insurance companies retreated on some downbeat feedback by route of analysts and fears that the scientific industry's woes would unfold to insurers.
The best stock among the 30 Dow industrials to lose greater than half a point become Philip Morris, probably the most energetic huge Board inventory, down three 1/2, to sixty four 1/2, below the carrying on with danger of greater tobacco and alcohol taxes to pay for the Clinton Administration's health-care plans.continue reading the leading story
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Mortality from cardiovascular disease (CVD) is increased in patients with non-Hodgkin lymphoma (NHL), according to a retrospective study published in Hematological Oncology.
Use of anthracycline-based chemotherapy and exposure to radiation therapy, both of which maintain been associated with an increased risk of CVD, are used in the treatment of some patients with NHL. Previous studies maintain identified an increased risk of CVD in patients with NHL, as well as a higher rate of CVD-related death in this population, although most of these studies focused on CVD morbidity. Hence, gaps remain regarding the relative risk of CVD mortality in patients with specific subtypes of NHL, such as the more aggressive diffuse big B-cell lymphoma (DLBCL) and the more indolent subtypes chronic lymphocytic lymphoma/small lymphocytic lymphoma (CLL/SLL) and follicular lymphoma (FL). In addition, specific risk factors for death from CVD in the patients with these NHL subtypes are unclear.
In this study, 153,983 patients with NHL including those with DLBCL (n=69,329), CLL/SLL (n=48,650) and FL (n=36,004) and corresponding information on race, marital status, antecedent of death, and prior radiation therapy were identified in the National Cancer Institute’s Surveillance, Epidemiology, and proximate Results (SEER) database for the era between January 2000 and November 2013. Data on CVD-related mortality for the general population was obtained from the Wide‐ranging Online Data for Epidemiologic Research (WONDER) implement from the Centers for Disease Control and Prevention. The primary proximate point was mortality from CVD.
At a median follow-up of 37 months, the rate of CVD-related mortality was 5.8% in the overall patient cohort, with an age-specific risk that was 14-fold higher than the general population. Within the 3 identified subtypes of NHL, 5.1%, 8.0%, and 4.4% of patients with DLBCL, CLL/SLL, and FL, respectively, died from CVD-related causes. Compared with the general population, the age-specific risks of CVD-related death in patients with CLL/SLL, FL, and DLBCL were 21-fold, 11-fold, and 13-fold higher, respectively.
Following adjustment for confounding factors, specific risk factors for mortality from CVD in patients with sum 3 identified subtypes of NHL included older age, manly gender, and residing in the southern US states, whereas white race and being married were associated with a lower risk of death from CVD. For patients with FL and DLBCL, another risk factor for CVD-related death was stage IV disease; in patients with these 2 subtypes of NHL, prior radiation therapy was associated with lower mortality from CVD.
Regarding the lower risk of CVD in patients with DLBCL compared with those with CLL/SLL, the study authors speculated that this finding may subsist related to the lower overall survival of the former group. In addition, they proposed that the association between higher disease stage and increased risk of CVD-related death may subsist related to an increased likelihood of receiving anthracycline-based chemotherapy for patients with more advanced disease. Furthermore, a decreased likelihood of receiving chemotherapy was offered as a practicable explanation for the finding of decreased CVD mortality risk in patients with a history of radiation therapy, although the authors stressed caution in the interpretation of those results.
Some of the limitations of this study identified by the study authors included want of information regarding administration of chemotherapy or known risk factors for CVD, such as smoking history, diabetes, and hypertension, as well as the possibility that mortality due to CVD is over-represented on death certificates.
“Our data suggest that risk assessment and careful cardiac monitoring are recommended for NHL patients, particularly those with the CLL/SLL subtypes,” the study authors concluded.
Reference Abuamsha H, Kadri AN, Hernandez AV. Cardiovascular mortality among patients with non-Hodgkin lymphoma: differences according to lymphoma subtype [published online March 27, 2019]. Hematol Oncol. doi: 10.1002/hon.2607
- By 2020, over 1.5 million people in the U.S. are likely to maintain dank AMD, the leading antecedent of blindness in industrialized countries
- Filing is based on aspect III data from the HAWK and HARRIER trials for brolucizumab
- Novartis used a priority review voucher to expedite review of brolucizumab in the U.S. and, if approved by FDA, anticipates launching by the proximate of 2019
EAST HANOVER, N.J., April 15, 2019 /PRNewswire/ -- Novartis announced that the U.S. Food and Drug Administration (FDA) accepted the company's Biologics License Application (BLA) for brolucizumab (RTH258) for the treatment of dank age-related macular degeneration (AMD), also known as neovascular AMD, or nAMD. Seeking to produce brolucizumab available as quickly as possible, Novartis used a priority review voucher to expedite FDA review. If approved by the FDA, Novartis anticipates launching brolucizumab by the proximate of 2019.
Estimates suggest that by 2020, 1.5 to 1.75 million people in the U.S. will subsist live with dank AMD, a leading antecedent of blindness worldwide and a rapidly growing public health concern1. As the disease progresses, patients may undergo loss of central vision, resulting in an inability to complete daily tasks. Without treatment, vision can rapidly deteriorate and may lead to blindness2.
"Reaching this milestone is an Important step in their efforts to reimagine the treatment journey for people with dank AMD and their caregivers," said Fabrice Chouraqui, President, Novartis Pharmaceuticals Corporation. "We are looking forward to the potential of a new option for patients with dank AMD, who often maintain to navigate considerable physical and emotional difficulties caused by deteriorating vision."
The regulatory application is primarily based on aspect III data from the HAWK and HARRIER trials — prospective, randomized, double-masked multi-center studies3,4. The primary endpoint of these studies was non-inferiority to aflibercept in imply change in best-corrected visual acuity (BCVA) from baseline to week 48 (mean change in BCVA of 6.6 letters for brolucizumab 6 mg versus 6.8 letters for aflibercept in HAWK and 6.9 letters versus 7.6 letters, respectively, in HARRIER). HAWK and HARRIER are the first and only global head-to-head trials in patients with dank AMD that prospectively demonstrated efficacy at week 48 starting with a 12-week dosing regimen.
Additionally, at week 48 in the studies, key secondary endpoint assessments showed significantly fewer brolucizumab patients with disease activity (23.5% of brolucizumab 6 mg patients versus 33.5% of aflibercept patients in HAWK, and 21.9% versus 31.4%, respectively, in HARRIER (P=0.0022 for both) as well as retinal fluid – key markers used by physicians to champion lead management of the disease in clinical practice (31% fewer patients on brolucizumab 6 mg had intra-retinal fluid (IRF) and/or sub-retinal fluid (SRF) in HAWK, and 26% fewer in HARRIER, versus aflibercept (P<0.0001 for both)5,6.
"Wet AMD robs people of their precious sight and takes a major toll on the lives of millions of people who visage not only vision loss, but also the affliction of frequent injections into their eyes," said Dawn Prall George, executive director, The champion Sight Foundation. "We are always excited about potential new treatment options and hopeful they may champion people manage this devastating disease."
About brolucizumab (RTH258)Brolucizumab (RTH258) is a humanized single-chain antibody fragment (scFv) and the most clinically advanced, humanized single-chain antibody fragment to gain this stage of development. Single-chain antibody fragments are highly sought after in drug progress due to their petite size, enhanced tissue penetration, rapid clearance from systemic circulation and drug delivery characteristics7-9.
The proprietary innovative structure results in a petite molecule (26 kDa) with potent inhibition of, and elevated affinity to, sum VEGF-A isoforms7,10. In preclinical studies, brolucizumab inhibited activation of VEGF receptors through prevention of the ligand-receptor interaction7,9,10. Increased signaling through the VEGF pathway is associated with pathologic ocular angiogenesis and retinal edema11. Inhibition of the VEGF pathway has been shown to inhibit the growth of neovascular lesions, resolve retinal edema and help vision in patients with chorioretinal vascular diseases12.
About HAWK and HARRIER study designWith more than 1,800 patients across nearly 400 sites worldwide, HAWK (NCT02307682) and HARRIER (NCT02434328) are the first and only global head-to-head trials in patients with nAMD that prospectively demonstrated efficacy at week 48 using an innovative q12w/q8w regimen, with a majority of patients on q12w immediately following the loading phase3-5. Both studies are 96-week prospective, randomized, double-masked multi-center studies and allotment of the aspect III clinical progress of brolucizumab3,4,6.
The studies were designed to compare the efficacy and safety of intravitreal injections of brolucizumab 6 mg (HAWK and HARRIER) and 3 mg (HAWK only) versus aflibercept 2 mg in patients with nAMD3,4. In both trials, patients were randomized to either brolucizumab or aflibercept3,4. Immediately following the 3-month loading phase, patients in the brolucizumab arms received a q12w dosing interval with an option to adjust to a q8w dosing interval based on masked disease activity assessments at defined visits3,4. Aflibercept was dosed bi-monthly according to its label at the time of study initiation3-6.
Brolucizumab met the primary efficacy objective of non-inferiority versus aflibercept in imply change in best-corrected visual acuity (BCVA) from baseline to week 48 with elevated statistical significance5. Additionally, brolucizumab demonstrated superiority in three secondary endpoints considered key parameters of nAMD: central subfield retinal thickness, retinal fluid (intraretinal fluid and/or subretinal fluid) and disease activity5.
At year two, the most frequent ocular adverse events (≥5% of patients in any treatment arm) for brolucizumab 3 mg, 6 mg and aflibercept, respectively, in HAWK were conjunctival hemorrhage (10.9%, 8.1% and 8.9%), reduced visual acuity (9.5%, 6.1% and 8.1%), vitreous floaters (7.3%, 6.1% and 4.4%), eye pain (7.8%, 5.0% and 5.8%), retinal hemorrhage (3.9%, 5.8% and 5.6%), cataract (5.0%, 5.6% and 3.6%), vitreous detachment (6.7%, 5.3% and 5.3%) and dehydrate eye (5.6%, 5.3% and 7.2%)5. The incidences of these events for brolucizumab 6 mg and aflibercept, respectively, in HARRIER were conjunctival hemorrhage (4.6% and 5.1%), reduced visual acuity (8.6% and 7.0%), vitreous floaters (4.1% and 1.4%), eye pain (3.5% and 5.1%), retinal hemorrhage (3.2% and 1.1%), cataract (3.0% and 11.7%), vitreous detachment (2.7% and 2.2%) and dehydrate eye (2.7% and 3.0%)6.
About neovascular age-related macular degeneration (nAMD or dank AMD) nAMD is the leading antecedent of strict vision loss and legal blindness in people over the age of 65 in North America, Europe, Australia and Asia, impacting an estimated 20 to 25 million people worldwide2,13. nAMD occurs when abnormal blood vessels form underneath the macula, the locality of the retina answerable for sharp, central vision. These blood vessels are delicate and leak fluid, disrupting the normal retinal architecture and ultimately causing damage to the macula1,14,15.
Early symptoms of nAMD include distorted vision or metamorphopsia and difficulties seeing objects clearly16. Prompt diagnosis and intervention are essential. As the disease progresses, cell damage increases, further reducing vision quality. This progression can lead to a complete loss of central vision, leaving the patient unable to read, drive or recognize intimate faces14. Without treatment, vision can rapidly deteriorate2.
About Novartis in ophthalmology Novartis Ophthalmology is reimagining the treatment and prevention of visual impairment and blindness. By pushing the boundaries of medicine and technology we're developing life-changing gene therapies, next-generation pharmaceuticals, and transformative technologies for diseases and conditions spanning every locality of eye disease, from the front to the back of the eye.
DisclaimerThis press release contains forward-looking statements within the acceptation of the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements can generally subsist identified by words such as "potential," "can," "will," "plan," "expect," "anticipate," "look forward," "believe," "committed," "investigational," "pipeline," "launch," or similar terms, or by express or implied discussions regarding potential marketing approvals, new indications or labeling for the investigational or approved products described in this press release, or regarding potential future revenues from such products. You should not locality undue reliance on these statements. Such forward-looking statements are based on their current beliefs and expectations regarding future events, and are theme to significant known and unknown risks and uncertainties. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those set forth in the forward-looking statements. There can subsist no guarantee that the investigational or approved products described in this press release will subsist submitted or approved for sale or for any additional indications or labeling in any market, or at any particular time. Nor can there subsist any guarantee that such products will subsist commercially successful in the future. In particular, their expectations regarding such products could subsist affected by, among other things, the uncertainties inherent in research and development, including clinical trial results and additional analysis of existing clinical data; regulatory actions or delays or government regulation generally; global trends toward health custody cost containment, including government, payor and general public pricing and reimbursement pressures and requirements for increased pricing transparency; their competence to obtain or maintain proprietary intellectual property protection; the particular prescribing preferences of physicians and patients; general political and economic conditions; safety, character or manufacturing issues; potential or actual data security and data privacy breaches, or disruptions of their information technology systems, and other risks and factors referred to in Novartis AG's current form 20-F on file with the US Securities and Exchange Commission. Novartis is providing the information in this press release as of this date and does not undertake any duty to update any forward-looking statements contained in this press release as a result of new information, future events or otherwise.
About Novartis Novartis is reimagining medicine to help and extend people's lives. As a leading global medicines company, they expend innovative science and digital technologies to create transformative treatments in areas of mighty medical need. In their quest to find new medicines, they consistently rank among the world's top companies investing in research and development. Novartis products gain more than 750 million people globally, and they are finding innovative ways to expand access to their latest treatments. About 105,000 people of more than 140 nationalities toil at Novartis around the world. Novartis Pharmaceuticals Corporation, a US affiliate of Novartis, is located in East Hanover, NJ. Find out more at www.novartis.com.
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Apr 11, 2019 (Heraldkeeper via COMTEX) -- APAC Xanthan Gum Market, dominated by China and India, is predicted to cross $491 million note by proximate of 2023 registering CAGR of more than 6.21% during forecast period. Increasing cosmetic and pharmaceutical industry establishments in the region due to growing regional claim along with low production costs can promote industry expansion.
Xanthan Gum Market size was more than 150 kilo tons for 2015 and is predicted to register more than 5.2% CAGR during forecast timeframe. Oil & Gas firms are actively involved in setting up enhanced oil recovery(EOR) methods to help crude oil & natural gas production from potential exhausting reserves that can propel industry expansion.Rising claim for food & beverages owing to snappily growing population and improved customer lifestyle in BRICS nations is predicted to fuel industry growth. Food & beverages segment was evaluated at more than $8.51 trillion for 2004 and crossed $15.1 trillion note for 2015. New products launched by firms like Kraft foods, Nestle and Udi is predicted to drive industry expansion.
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Increasing significance of cosmetic items like lotions, denture cleaners and shampoos along with growing consciousness about risks associated with synthetic personal custody items are predicted to propel xanthan gum market globally. Cosmetic segment was evaluated at $156 billion for 2006 and surpassed $221 billion for 2015 registering CAGR of more than 3.51% CAGR. Expansion of the segment is credited to factors like surge in veteran age population and climatic changes along with rising concerns about hygiene and personal health in countries like India and China.
Sanction from regulatory authorities like FDA(U.S. Food & Drug Administration) and USDA(U.S. Department of Agriculture)for expend of Xanthan gum in drugs & bakery items is predicted to boost xanthan gum market expansion. In addition to this, approval by European commission of its expend as thickener, emulsifier, gelling agent and stabilizer in food & beverage segment has further driven the industry growth.
Gaur gum is a righteous substitute for Xanthan gum as it displays advantageous features like elevated solubility and viscosity. Growing significance of guar gum applications in food & beverage segment and hydraulic fracturing can block the industry claim and adversely move xanthan gum market cost trends.
Global xanthan gum market is segmented into various applications food & beverage applications, oil & gas applications and pharmaceutical applications. Food & beverage segment is predicted to register more than 6.1% CAGR in terms of revenue. The growth of the segment can subsist credited to growing moisture retaining product competence and its capacity to obstruct staling resulting in enhanced shelf life span of baked products.
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Oil & gas segment was evaluated at more than $301 million for 2015. Extensive utilization of horizontal drilling methods and claim for drilled solids can fuel industry expansion during forecast timeline. Rising global refinery production is predicted to favorably move industry growth.
Pharmaceutical segment is predicted to cross $55.1 million note by proximate of 2023 registering CAGR of more than 5.3% during forecast timeline. These applications act as protective suspension colloids, diluting agents and tablet disintegrants. Further, synthetic detail substitution by natural gum is predicted to enhance xanthan gum market share.
The industry is segmented into key geographical regions like North America, APAC, Europe, Latin America and MEA. North America , dominated by U.S Xanthan gum market share, was valued at higher than $220 million for 2015. Rapid recovery of pharmaceutical segment in U.S. due to big scale expenditure on drugs can create favorable effect on product demand.
European industry is predicted to register more than 5.1% CAGR in terms of revenue. Increasing claim for personal custody items in UK, Germany, France and Italy can favorably move claim and growth of industry in the region. Further, growing spending on research & progress activities in pharmaceutical segment can fuel claim of the product in Europe.
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Key xanthan gum market players profiled in the report include Deosen Biochemical limited, CP Kelco, Qingdao Unionchem Company Limited, Gum Technology Corporation, Jungbunzlauer, Meihua Holdings Group Company Limited, Cargill, Fufeng Group Company Limited, Hebei Xinhe Biochemical Company Limited, Pfizer Incorporation, DuPont Danisco, Sancho & Lee Company Limited and Solvay Group.
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Global Market Insights, Inc., headquartered in Delaware, U.S., is a global market research and consulting service provider; offering syndicated and custom research reports along with growth consulting services. Their trade intelligence and industry research reports proffer clients with penetrative insights and actionable market data specially designed and presented to aid strategic conclusion making. These exhaustive reports are designed via a proprietary research methodology and are available for key industries such as chemicals, advanced materials, technology, renewable energy and biotechnology.
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